Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382372 | 0.80 | DRD3 (0.34) | ALDH1A1MAPT | |
| SCHEMBL9387685 | 0.73 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL8449850 | 0.73 | DGAT1 (0.45) | ALDH1A1MAPT | |
| SCHEMBL1998038 | 0.72 | FKBP1A (0.32) | — | |
| SCHEMBL1991216 | 0.72 | GBA1 (0.33) | MAPT | |
| SCHEMBL8324468 | 0.72 | GBA1 (0.33) | MAPT | |
| SCHEMBL9387801 | 0.72 | SLC6A2 (0.32) | — | |
| SCHEMBL8319230 | 0.71 | HTT (0.38) | ALDH1A1MAPT | |
| SCHEMBL6015851 | 0.71 | HTT (0.38) | ALDH1A1MAPT | |
| SCHEMBL1999145 | 0.71 | BUB1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384349-B1 | Substituted pyrroles | HOFFMANN LA ROCHE (CH) | 1994-04-27 | — | — | EP | disclosed |
| EP-0384349-A1 | Substituted pyrroles | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-29 | — | — | EP | disclosed |