Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673785 | 0.85 | ALDH1A1 (0.60) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL2593397 | 0.85 | ALDH1A1 (0.60) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL30875697 | 0.84 | SMN1; SMN2 (0.52) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL8867665 | 0.84 | SMN1; SMN2 (0.52) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL8867650 | 0.82 | ALDH1A1 (0.50) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL2350911 | 0.81 | ALDH1A1 (0.58) | MAPTCYP1A2CYP3A4CYP2C19FFAR1 | |
| SCHEMBL9385245 | 0.81 | CYP1A2 (0.56) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL8790409 | 0.81 | TSHR (0.55) | MAPTFFAR1SMN1; SMN2KMT2AFFAR4 | |
| SCHEMBL10410570 | 0.81 | KDM4E (0.60) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL704754 | 0.80 | TTR (0.64) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |