SCHEMBL9384261

SCHEMBL9384261

CCOC(=O)N(N)C(=O)C(Sc1nc(OC)cc(OC)n1)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
ADORA3 P0DMS8 2/20 0.35
ADORA1 P30542 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
EDNRB P24530 2/20 0.32
EDNRA P25101 2/20 0.32
LMNA P02545 1/20 0.31
PRNP P04156 1/20 0.31
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9389557 0.86 ADORA3 (0.37) ALDH1A1ADORA3ADORA1EDNRBEDNRA
SCHEMBL9388381 0.86 ALDH1A1 (0.34) ALDH1A1KDM4EEDNRBEDNRA
SCHEMBL9386258 0.80 ALDH1A1 (0.36) ALDH1A1KDM4EEDNRBEDNRALMNA
SCHEMBL9386424 0.79 EDNRB (0.38) ALDH1A1KDM4EMAPTEDNRBEDNRA
SCHEMBL9384636 0.77 ALDH1A1 (0.36) ALDH1A1ADORA3ADORA1EDNRBEDNRA
SCHEMBL9385181 0.77 MAPT (0.34) ALDH1A1KDM4EMAPTPOLBEDNRB
SCHEMBL8943560 0.77 ALDH1A1 (0.41) ALDH1A1ADORA3ADORA1KDM4EMAPT
SCHEMBL8943363 0.76 ALDH1A1 (0.40) ALDH1A1ADORA3ADORA1KDM4EMAPT
SCHEMBL9389519 0.76 PTGES (0.40) EDNRBEDNRAALOX5
SCHEMBL9082340 0.75 ADORA3 (0.40) ALDH1A1ADORA3ADORA1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0588194-A2 Hydrazones and their use as herbicides NIHON BAYER AGROCHEM K.K. (JP) 1994-03-23 EP disclosed