Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9388181 | 0.97 | KCNJ1 (0.50) | KCNJ1KCNH2BCHEATML3MBTL1 | |
| SCHEMBL9388604 | 0.84 | KMT2A (0.60) | KCNJ1KCNH2HRH1HTR1AMAPT | |
| SCHEMBL9386459 | 0.84 | LTA4H (0.58) | KCNJ1KCNH2HRH1MAPTKMT2A | |
| SCHEMBL9384076 | 0.83 | POLB (0.57) | HRH1HTR1AMAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9384427 | 0.83 | LTA4H (0.57) | KCNJ1KCNH2HRH1MAPTKMT2A | |
| SCHEMBL9431507 | 0.82 | HRH1 (0.44) | ATMHRH1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9384967 | 0.82 | POLB (0.56) | HRH1HTR1AMAPTKMT2AMEN1 | |
| SCHEMBL9383742 | 0.82 | ALDH1A1 (0.50) | L3MBTL1MAPTALDH1A1 | |
| SCHEMBL9383669 | 0.81 | HRH3 (0.57) | HRH1HTR1AMAPTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9384859 | 0.81 | ALDH1A1 (0.49) | L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |