Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SOD1 | P00441 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384076 | 0.90 | POLB (0.57) | KMT2AHTR1AHRH1POLBMEN1 | |
| Hydrochloric Acid SCHEMBL9384967 | 0.89 | POLB (0.56) | KMT2AHTR1AHRH1POLBMEN1 | |
| SCHEMBL9383742 | 0.84 | ALDH1A1 (0.50) | POLBALDH1A1MAPT | |
| SCHEMBL9384356 | 0.84 | KCNJ1 (0.53) | KMT2AHTR1AHRH1MEN1ALDH1A1 | |
| SCHEMBL9429593 | 0.84 | SOD1 (0.57) | KMT2AHTR1AHRH1MEN1ALDH1A1 | |
| SCHEMBL9429398 | 0.84 | HTR1A (0.56) | KMT2AHTR1AHRH1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9384859 | 0.83 | ALDH1A1 (0.49) | POLBALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9428830 | 0.83 | ALDH1A1 (0.56) | KMT2AHTR1AHRH1ALDH1A1MAPT | |
| SCHEMBL9384620 | 0.82 | KCNJ1 (0.64) | KCNJ1KCNH2 | |
| Oxalic Acid SCHEMBL9388181 | 0.82 | KCNJ1 (0.50) | KMT2AHTR1AHRH1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |