Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385558 | 0.95 | ADRB3 (0.51) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| Hydrochloric Acid SCHEMBL9385514 | 0.91 | ADRB1 (0.60) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL9385563 | 0.84 | KCNH2 (0.53) | ADRB2ADRB1ADRB3KCNH2HTR1A | |
| SCHEMBL9389027 | 0.80 | DRD2 (0.57) | KCNH2 | |
| Hydrochloric Acid SCHEMBL9384659 | 0.80 | ADRB1 (0.58) | ADRB2ADRB1ADRB3KCNH2HTR1A | |
| SCHEMBL9385595 | 0.79 | ADRB3 (0.63) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL10591968 | 0.79 | ADRB1 (0.55) | ADRB2ADRB1ADRB3HTR1AOPRK1 | |
| Hydrochloric Acid SCHEMBL9385006 | 0.79 | ADRB3 (0.67) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL9385521 | 0.78 | ADRB2 (0.49) | ADRB2ADRB1ADRB3KCNH2SLC6A2 | |
| SCHEMBL9386170 | 0.77 | ADRB2 (0.49) | ADRB2ADRB1ADRB3KCNH2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003425-A2 | CARBOSTYRIL DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIA | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |