Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387266 | 0.88 | NPSR1 (0.36) | HRH1KDM4ENPSR1TDP1KMT2A | |
| SCHEMBL9387418 | 0.83 | NOS2 (0.39) | HRH1KDM4ENPSR1TDP1POLB | |
| SCHEMBL9536209 | 0.83 | SSTR5 (0.47) | HRH1SMN1; SMN2KMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL9537265 | 0.81 | SSTR5 (0.46) | HRH1SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL9386904 | 0.80 | KDM4E (0.42) | KDM4EPOLBTSHRKMT2AMEN1 | |
| SCHEMBL9382748 | 0.79 | MEN1 (0.50) | HRH1KDM4ETDP1TSHRKMT2A | |
| Acetic Acid SCHEMBL9593584 | 0.75 | ALDH1A1 (0.46) | KDM4EKMT2AMEN1 | |
| SCHEMBL9383332 | 0.75 | KCNH2 (0.44) | POLBTSHR | |
| SCHEMBL9536155 | 0.73 | USP2 (0.42) | HRH1KDM4ENPSR1TDP1POLB | |
| SCHEMBL8565529 | 0.73 | GRIN2B (0.38) | HRH1KDM4ENPSR1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393738-B1 | Hydroxyalkylfuranyl derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1994-11-30 | — | — | EP | disclosed |
| US-5272150-A | Hydroxyalkylfuranyl derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-12-21 | — | — | US | disclosed |