Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | CTSV | O60911 | 5/20 | 0.58 |
| ▸ | CTSL | P07711 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12090863 | 0.77 | CTSV (0.56) | HPGDCTSVCTSLLMNAKDM4E | |
| SCHEMBL308319 | 0.76 | GSK3B (0.61) | HPGDLMNAKDM4ETP53RAB9A | |
| SCHEMBL29470995 | 0.76 | GSK3B (0.61) | HPGDLMNAKDM4ETP53RAB9A | |
| SCHEMBL1988750 | 0.75 | KDM4E (0.58) | HPGDLMNAKDM4ETP53HSD17B10 | |
| SCHEMBL6001723 | 0.75 | CTSV (0.75) | HPGDCTSVCTSLLMNAKDM4E | |
| Carbazole SCHEMBL28334621 | 0.75 | KDM4E (0.61) | HPGDLMNAKDM4ETP53NPSR1 | |
| Carbazole SCHEMBL12099644 | 0.75 | KDM4E (0.61) | HPGDLMNAKDM4ETP53NPSR1 | |
| SCHEMBL4772827 | 0.74 | ALDH1A1 (0.97) | HPGDLMNAKDM4ETP53NPSR1 | |
| SCHEMBL31718101 | 0.74 | ALDH1A1 (0.97) | HPGDLMNAKDM4ETP53NPSR1 | |
| SCHEMBL29411863 | 0.74 | HPGD (1.00) | HPGDCTSVCTSLLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002145-A2 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 1994-02-03 | — | — | WO | disclosed |