Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282500 | 0.81 | NOS3 (0.41) | ALDH1A1OGATGFBR1KDM4EMAPT | |
| SCHEMBL27499514 | 0.81 | ALDH1A1 (0.39) | ALDH1A1OGAMEN1CASP1CASP7 | |
| SCHEMBL30893589 | 0.81 | NOS3 (0.41) | ALDH1A1OGATGFBR1KDM4EMAPT | |
| SCHEMBL3970945 | 0.81 | ALDH1A1 (0.39) | ALDH1A1OGARECQLMEN1CASP1 | |
| SCHEMBL12985992 | 0.79 | NAPRT (0.50) | ALDH1A1RECQLMEN1KMT2AKDM4E | |
| SCHEMBL23098879 | 0.78 | CALM1 (0.43) | ALDH1A1MAPT | |
| SCHEMBL27670775 | 0.78 | TDP1 (0.38) | ALDH1A1OGAMEN1CASP1CASP7 | |
| SCHEMBL12985473 | 0.78 | MAOB (0.47) | RECQL | |
| SCHEMBL19251597 | 0.77 | OGA (0.39) | ALDH1A1OGAKDM4EPDE10A | |
| SCHEMBL24176501 | 0.77 | OGA (0.41) | ALDH1A1OGAMEN1CASP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |