Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386979 | 0.91 | SLC6A4 (0.52) | SLC6A4HRH3SLC6A2SLC6A3GBA1 | |
| SCHEMBL11400538 | 0.78 | SLC6A4 (0.61) | SLC6A4HRH3NAMPTGBA1 | |
| SCHEMBL11539374 | 0.78 | SLC6A4 (0.53) | SLC6A4SLC6A2 | |
| SCHEMBL18404328 | 0.77 | EED (0.42) | SLC6A4HRH3SLC6A2SLC6A3GBA1 | |
| SCHEMBL8521048 | 0.75 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3GBA1RBP4 | |
| SCHEMBL3143212 | 0.74 | SLC6A4 (0.39) | SLC6A4HRH3SLC6A2SLC6A3 | |
| SCHEMBL82734 | 0.74 | GBA1 (0.61) | SLC6A4HRH3GBA1 | |
| SCHEMBL9387232 | 0.73 | KCNH2 (0.54) | HRH3 | |
| SCHEMBL7987100 | 0.72 | LMNA (0.51) | SLC6A4SLC6A2SLC6A3NAMPT | |
| Hydrochloric Acid SCHEMBL7669421 | 0.72 | GBA1 (0.59) | SLC6A4HRH3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994001403-A1 | PIPERIDINE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-01-20 | — | — | WO | disclosed |