Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258873 | 0.93 | NLRP3 (0.39) | LMNAALDH1A1NLRP3MAPTTLR4 | |
| SCHEMBL7938425 | 0.85 | DGKA (0.47) | LMNAALDH1A1NLRP3PAMMAPT | |
| SCHEMBL11762251 | 0.83 | TLR4 (0.41) | NLRP3PAMTLR4 | |
| SCHEMBL9653338 | 0.83 | NLRP3 (0.33) | NLRP3 | |
| SCHEMBL1374575 | 0.80 | TLR4 (0.42) | NLRP3PAMTLR4 | |
| SCHEMBL11576115 | 0.78 | FFAR3 (0.46) | ALDH1A1FFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL10071457 | 0.77 | NLRP3 (0.43) | ALDH1A1NLRP3MAPTTLR4 | |
| SCHEMBL1471700 | 0.75 | DGKA (0.53) | LMNAALDH1A1NLRP3PAMMAPT | |
| SCHEMBL11129832 | 0.74 | HTR2C (0.50) | ALDH1A1PAM | |
| SCHEMBL23848928 | 0.73 | TLR4 (0.48) | NLRP3TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133296-A | Moisture-resistant PBO fiber and articles, and method of making | HONEYWELL INT INC (US) | 2008-02-27 | — | — | CN | disclosed |
| WO-1994004582-A1 | NOVEL EPOXY RESIN CURE CATALYST | S/S PERFORMANCE PRODUCTS, INC. (US) | 1994-03-03 | — | — | WO | disclosed |
| EP-0014745-B1 | CURING AGENT FOR POLYEPOXIDES, CURABLE EPOXY RESIN COMPOSITIONS, HARDENED PRODUCTS THEREFROM AND PROCESS FOR CURING A POLYEPOXIDE | DIAMOND SHAMROCK CORPORATION (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0075827-A2 | Polyepoxide curing by polymercaptans plus catalytic co-curing agents | DIAMOND SHAMROCK CHEMICALS COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |
| EP-0014745-A1 | Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide | DIAMOND SHAMROCK CORPORATION (US) | 1980-09-03 | — | — | EP | disclosed |
| US-4177173-A | INFUSIBLE FILMS, CASTINGS OR ADHESIVES | DIAMOND SHAMROCK CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |