SCHEMBL258873

SCHEMBL258873

CCCC1OC1COC(=O)CCC(=O)OCC1OC1CCC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 2/20 0.39
ALDH1A1 P00352 2/20 0.37
DGKA P23743 1/20 0.34
MAPT P10636 1/20 0.34
TLR4 O00206 1/20 0.34
LPAR1 Q92633 3/20 0.33
LPAR3 Q9UBY5 3/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9387162 0.93 LMNA (0.44) NLRP3ALDH1A1MAPTTLR4LMNA
SCHEMBL7938425 0.91 DGKA (0.47) NLRP3ALDH1A1DGKAMAPTLPAR1
SCHEMBL11762251 0.89 TLR4 (0.41) NLRP3DGKATLR4LPAR1LPAR3
SCHEMBL9653338 0.89 NLRP3 (0.33) NLRP3LPAR1LPAR3
SCHEMBL1374575 0.85 TLR4 (0.42) NLRP3DGKATLR4LPAR1LPAR3
SCHEMBL10071457 0.82 NLRP3 (0.43) NLRP3ALDH1A1DGKAMAPTTLR4
SCHEMBL1471700 0.81 DGKA (0.53) NLRP3ALDH1A1DGKAMAPTLPAR1
SCHEMBL8972452 0.79 PRKCA (0.40) NLRP3ALDH1A1DGKAMAPTTLR4
SCHEMBL9591645 0.79 PRKCA (0.40) NLRP3ALDH1A1DGKAMAPTTLR4
SCHEMBL23848928 0.79 TLR4 (0.48) NLRP3DGKATLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018160726-A1 LOW DIELECTRIC CONSTANT POROUS EPOXY-BASED DIELECTRIC GEORGIA TECH RESEARCH CORPORATION (US) 2018-09-07 WO claimed
US-7517943-B2 Golf ball layer compositions formed from oxirane functional endcapped polymers ACUSHNET COMPANY (US) 2009-04-14 US claimed
US-20070129510-A1 Golf ball layer compositions formed from oxirane functional endcapped polymers ACUSHNET COMPANY 2007-06-07 US claimed
US-5552208-A High strength composite ALLIEDSIGNAL INC. (US) 1996-09-03 US claimed
US-12613209-B2 Embedded sensor system for measurement and monitoring of the pore solution electrical resistivity in concrete materials and structures THE PENN STATE RESEARCH FOUNDATION (PA) 2026-04-28 US disclosed
US-20240230568-A1 EMBEDDED SENSOR SYSTEM FOR MEASUREMENT AND MONITORING OF THE PORE SOLUTION ELECTRICAL RESISTIVITY IN CONCRETE MATERIALS AND STRUCTURES PENN STATE RES FOUND (US) 2024-07-11 US disclosed
WO-2022240963-A2 EMBEDDED SENSOR SYSTEM FOR MEASUREMENT AND MONITORING OF THE PORE SOLUTION ELECTRICAL RESISTIVITY IN CONCRETE MATERIALS AND STRUCTURES THE PENN STATE RESEARCH FOUNDATION (US) 2022-11-17 WO disclosed
WO-2018160726-A1 LOW DIELECTRIC CONSTANT POROUS EPOXY-BASED DIELECTRIC GEORGIA TECH RESEARCH CORPORATION (US) 2018-09-07 WO disclosed
US-20180243967-A1 BALLISTIC PLATE MATERIALS AND METHOD MYSTERY RANCH, LTD. 2018-08-30 US disclosed
US-20170234657-A1 BALLISTIC PLATE MATERIALS AND METHOD MYSTERY RANCH, LTD. 2017-08-17 US disclosed
EP-1585853-B1 BI-DIRECTIONAL AND MULTI-AXIAL FABRICS AND FABRIC COMPOSITES HONEYWELL INT INC (US) 2016-10-05 EP disclosed
US-8132494-B1 Ballistic resistant composite article having improved matrix system HONEYWELL INTERNATIONAL, INC. (US) 2012-03-13 US disclosed
US-4235974-A Process for the production of epoxy cellular solid products BLOUNT DAVID H 1980-11-25 US disclosed
EP-0014745-A1 Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide DIAMOND SHAMROCK CORPORATION (US) 1980-09-03 EP disclosed
US-4177173-A INFUSIBLE FILMS, CASTINGS OR ADHESIVES DIAMOND SHAMROCK CORPORATION (US) 1979-12-04 US disclosed
US-4118535-A SOLVENTLESS-DRY POWDER COATINGS, FILAMENTS, FIBERS, FILMS, MOLDING COMPOUNDS GENERAL ELECTRIC COMPANY (US) 1978-10-03 US disclosed
US-4066625-A CURING AGENTS AMICON CORPORATION (US) 1978-01-03 US disclosed
US-4034014-A FROM MALEIC MONOMERS AND ALKYLSTYRENES ALLIED CHEMICAL CORPORATION (US) 1977-07-05 US disclosed
US-3960813-A ADNC BLENDSADIPODI(NITRILE CARBONATE) ATLANTIC RICHFIELD COMPANY (US) 1976-06-01 US disclosed
US-3948855-A Process for reacting a phenol with a vicinal epoxy compound in the presence of phosphorus or carbon containing acid, ester or acid ester THE DOW CHEMICAL COMPANY (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12613209-B2 Embedded sensor system for measurement and monitoring of the pore solution electrical resistivity in concrete materials and structures PIEZO1, SLC9A2, SLC11A2 NLRP3 367/4885ALDH1A1 4783/4885DGKA 3962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.