Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756774 | 0.77 | ALDH1A1 (0.34) | CYP1A2KDM4ETSHRVDRL3MBTL1 | |
| SCHEMBL28060735 | 0.76 | CYP1A2 (0.51) | MEN1KMT2ACYP1A2KDM4ETSHR | |
| SCHEMBL909723 | 0.75 | MEN1 (0.46) | MEN1KMT2AKDM4ECYP3A4CYP2D6 | |
| SCHEMBL9820099 | 0.74 | MEN1 (0.45) | MEN1KMT2ACYP1A2KDM4ECYP3A4 | |
| SCHEMBL4958838 | 0.74 | PRMT5 (0.44) | MEN1KMT2ACYP3A4CYP2D6TSHR | |
| SCHEMBL27653272 | 0.73 | MEN1 (0.39) | MEN1KMT2ACYP1A2KDM4ECYP3A4 | |
| SCHEMBL16759739 | 0.73 | MEN1 (0.39) | MEN1KMT2AKDM4ECYP3A4CYP2D6 | |
| SCHEMBL6605222 | 0.72 | MEN1 (0.45) | MEN1KMT2ACYP1A2KDM4ECYP3A4 | |
| SCHEMBL1700674 | 0.72 | MEN1 (0.44) | MEN1KMT2AKDM4ECYP3A4CYP2D6 | |
| SCHEMBL30988955 | 0.72 | MEN1 (0.44) | MEN1KMT2AKDM4ECYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003466-A1 | ACYCLIC PURINE PHOSPHONATE NUCLEOTIDE ANALOGS AS ANTIVIRAL AGENTS, AND RELATED SYNTHETIC METHODS | SRI INTERNATIONAL (US) | 1994-02-17 | — | — | WO | disclosed |