Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140993 | 0.92 | KMT2A (0.43) | CYP1A2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL6903086 | 0.86 | KMT2A (0.40) | CYP1A2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL6156140 | 0.84 | CASP1 (0.43) | CYP1A2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL6154454 | 0.81 | POLB (0.41) | CYP1A2LMNAMEN1KMT2AESR1 | |
| SCHEMBL6157266 | 0.80 | ALDH1A1 (0.39) | CYP1A2LMNAMEN1KMT2AESR1 | |
| SCHEMBL10916647 | 0.80 | MEN1 (0.41) | CYP1A2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL6982217 | 0.80 | LMNA (0.44) | CYP1A2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7340052 | 0.80 | POLB (0.49) | CYP1A2KDM4EMEN1KMT2AESR1 | |
| SCHEMBL6154515 | 0.79 | POLB (0.37) | CYP1A2LMNAMEN1KMT2AESR1 | |
| SCHEMBL8216091 | 0.79 | TK1 (0.46) | CYP1A2MEN1KMT2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105378029-A | Hydrophilic high quantum yield acridinium esters with improved stability and fast luminescence | SIEMENS HEALTHCARE DIAGNOSTICS INC | 2016-03-02 | — | — | CN | disclosed |