Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388244 | 0.84 | TP53 (0.42) | SMN1; SMN2CYP1A2TP53GLAMAPT | |
| SCHEMBL9388237 | 0.79 | ADORA3 (0.41) | ALDH1A1ADORA3ADORA1 | |
| SCHEMBL9384283 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1TP53KDM4E | |
| SCHEMBL9389241 | 0.77 | EDNRB (0.38) | SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9755676 | 0.77 | PPARA (0.47) | LMNASMN1; SMN2ALDH1A1ADORA3CYP1A2 | |
| SCHEMBL13851482 | 0.77 | ALOX5 (0.44) | LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL9082975 | 0.77 | ALOX5 (0.44) | LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL13851483 | 0.77 | ALOX5 (0.44) | LMNAALDH1A1CYP1A2KDM4E | |
| SCHEMBL16160330 | 0.77 | CYP1A2 (0.44) | LMNASMN1; SMN2ALDH1A1ADORA3CYP1A2 | |
| SCHEMBL9383856 | 0.76 | EDNRB (0.39) | LMNASMN1; SMN2ALDH1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588194-A2 | Hydrazones and their use as herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-23 | — | — | EP | disclosed |