Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388253 | 0.84 | LMNA (0.38) | TP53GLAMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9383783 | 0.76 | NPSR1 (0.36) | SMN1; SMN2NPSR1 | |
| SCHEMBL9384283 | 0.74 | SMN1; SMN2 (0.37) | TP53SMN1; SMN2 | |
| SCHEMBL9389241 | 0.74 | EDNRB (0.38) | SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9082975 | 0.74 | ALOX5 (0.44) | CYP1A2 | |
| SCHEMBL13851482 | 0.74 | ALOX5 (0.44) | CYP1A2 | |
| SCHEMBL13851483 | 0.74 | ALOX5 (0.44) | CYP1A2 | |
| SCHEMBL9388237 | 0.74 | ADORA3 (0.41) | KMT2A | |
| SCHEMBL9384049 | 0.73 | EPHX1 (0.34) | SMN1; SMN2 | |
| SCHEMBL9383856 | 0.73 | EDNRB (0.39) | MAPTSMN1; SMN2MEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588194-A2 | Hydrazones and their use as herbicides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-23 | — | — | EP | disclosed |