Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | TKT | P29401 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22558708 | 0.90 | L3MBTL1 (0.51) | L3MBTL1POLBMAPK1MAPTCACNA1G | |
| SCHEMBL30484228 | 0.86 | L3MBTL1 (0.57) | L3MBTL1POLBMAPK1MAPTCACNA1G | |
| SCHEMBL9388169 | 0.86 | L3MBTL1 (0.57) | L3MBTL1POLBMAPK1MAPTCACNA1G | |
| SCHEMBL2145798 | 0.83 | L3MBTL1 (0.50) | L3MBTL1POLBMAPK1MAPTCACNA1G | |
| SCHEMBL21503629 | 0.83 | L3MBTL1 (0.50) | L3MBTL1POLBMAPK1MAPTCACNA1G | |
| SCHEMBL20195263 | 0.83 | L3MBTL1 (0.36) | L3MBTL1MAPT | |
| SCHEMBL30942648 | 0.81 | CA2 (0.38) | L3MBTL1MAPT | |
| SCHEMBL22558739 | 0.80 | L3MBTL1 (0.50) | L3MBTL1POLBMAPK1MAPTCACNA1G | |
| SCHEMBL3890599 | 0.79 | L3MBTL1 (0.53) | L3MBTL1POLBMAPK1MAPTCACNA1G | |
| SCHEMBL12470245 | 0.79 | L3MBTL1 (0.53) | L3MBTL1POLBMAPK1MAPTCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914597-B1 | PYRAZOLOPYRIDINE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC (JP) | 2017-12-06 | — | — | EP | disclosed |
| WO-1994004527-A1 | PYRIDYLETHOXY-, PYRIDYLETHYLAMINO-, AND PYRIDYLPROPYL-DERIVATIVES OF QUINOLINE AND QUINAZOLINE AS INSECTICIDES AND FUNGICIDES | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |