Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388917 | 0.83 | L3MBTL1 (0.54) | L3MBTL1MAPT | |
| SCHEMBL20195282 | 0.79 | PPARA (0.33) | CA2CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL20195208 | 0.79 | PPARA (0.40) | CA2CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL30942648 | 0.77 | CA2 (0.38) | L3MBTL1CA2CYP4F2CYP4A11KDM4E | |
| SCHEMBL20195249 | 0.77 | MAPT (0.50) | L3MBTL1CA2CYP4F2CYP4A11KDM4E | |
| SCHEMBL20195262 | 0.76 | CA2 (0.32) | CA2 | |
| SCHEMBL3229511 | 0.75 | NNMT (0.44) | CYP4F2CYP4A11KDM4EMAPTPIK3CA | |
| SCHEMBL23309220 | 0.75 | DGAT1 (0.55) | L3MBTL1CYP4F2CYP4A11PPARA | |
| SCHEMBL20195254 | 0.75 | ACACB (0.42) | L3MBTL1CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL22558708 | 0.74 | L3MBTL1 (0.51) | L3MBTL1CYP4F2CYP4A11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729447-B1 | POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR | H LUNDBECK AS (DK) | 2018-05-30 | — | — | EP | disclosed |