Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 8/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DDO | Q99489 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393346 | 0.80 | DAO (0.49) | DAOKDM4EDYRK1ATDP1DDO | |
| SCHEMBL9388997 | 0.80 | DAO (0.66) | DAOKDM4ETDP1DDOPLA2G7 | |
| SCHEMBL9389395 | 0.80 | KDM4E (0.46) | DAOKDM4ETDP1DDOPLA2G7 | |
| SCHEMBL8583717 | 0.80 | DAO (0.66) | DAOKDM4ETDP1DDOPLA2G7 | |
| SCHEMBL16767858 | 0.79 | DAO (1.00) | DAODDO | |
| SCHEMBL9390027 | 0.78 | DAO (0.68) | DAOKDM4ETDP1DDOPLA2G7 | |
| SCHEMBL9389023 | 0.76 | DAO (0.45) | DAOKDM4ETDP1DDOTP53 | |
| SCHEMBL9389330 | 0.76 | KDM4E (0.43) | DAOKDM4ETDP1DDOPLA2G7 | |
| SCHEMBL9389819 | 0.76 | KIF11 (0.47) | DAOKDM4ETDP1DDOPLA2G7 | |
| SCHEMBL2269012 | 0.76 | KDM4E (0.64) | DAOKDM4EDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |