Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 8/20 | 0.66 |
| ▸ | DDO | Q99489 | 4/20 | 0.66 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362656 | 0.80 | DAO (0.61) | DAODDO | |
| SCHEMBL9389846 | 0.80 | DAO (0.49) | DAODDOPLA2G7KDM4ETDP1 | |
| SCHEMBL9393346 | 0.80 | DAO (0.49) | DAODDOPLA2G7KDM4ETDP1 | |
| SCHEMBL9389416 | 0.80 | DAO (0.66) | DAODDOPLA2G7KDM4ETDP1 | |
| SCHEMBL9389395 | 0.80 | KDM4E (0.46) | DAODDOPLA2G7KDM4ETDP1 | |
| SCHEMBL8583717 | 0.80 | DAO (0.66) | DAODDOPLA2G7KDM4ETDP1 | |
| SCHEMBL3362300 | 0.79 | DAO (1.00) | DAODDO | |
| SCHEMBL9390027 | 0.78 | DAO (0.68) | DAODDOPLA2G7KDM4ETDP1 | |
| SCHEMBL9389023 | 0.76 | DAO (0.45) | DAODDOPLA2G7KDM4ETDP1 | |
| SCHEMBL9389819 | 0.76 | KIF11 (0.47) | DAODDOPLA2G7KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |