SCHEMBL8274381

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14088919	1.00	MAPT (0.51)	MAPTSMN1; SMN2HTTKDM4EALDH1A1
	SCHEMBL18767289	0.82	HDAC4 (0.40)	MAPTSMN1; SMN2HDAC4HDAC2HDAC8
	SCHEMBL2165184	0.81	RECQL (0.55)	MAPTSMN1; SMN2HTTKDM4EALDH1A1
	SCHEMBL746313	0.81	RECQL (0.55)	MAPTSMN1; SMN2HTTKDM4EALDH1A1
	SCHEMBL29942690	0.81	HDAC4 (0.39)	MAPTSMN1; SMN2HDAC4HDAC2HDAC8
	SCHEMBL23752855	0.81	HDAC4 (0.39)	MAPTSMN1; SMN2HDAC4HDAC2HDAC8
	SCHEMBL746312	0.81	RECQL (0.55)	MAPTSMN1; SMN2HTTKDM4EALDH1A1
	SCHEMBL23752854	0.81	HDAC4 (0.39)	MAPTSMN1; SMN2HDAC4HDAC2HDAC8
	Methylamine SCHEMBL9389458	0.80	RECQL (0.55)	MAPTSMN1; SMN2HTTKDM4EKMT2A
	SCHEMBL11339460	0.79	HTT (0.59)	MAPTSMN1; SMN2HTTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.