Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394475 | 0.94 | L3MBTL1 (0.47) | L3MBTL1MAPTNPSR1ATMHPGD | |
| SCHEMBL8310193 | 0.87 | GAA (0.49) | L3MBTL1MAPTHPGDMEN1KMT2A | |
| SCHEMBL9133505 | 0.82 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL4592851 | 0.79 | KMT2A (0.46) | MAPTHPGDKMT2AKDM4EALDH1A1 | |
| SCHEMBL28197534 | 0.79 | IDO1 (0.38) | L3MBTL1HPGDKMT2AALDH1A1TSHR | |
| SCHEMBL5420692 | 0.79 | L3MBTL1 (0.71) | L3MBTL1MAPTNPSR1ATMHPGD | |
| SCHEMBL9390803 | 0.76 | MAPK1 (0.36) | L3MBTL1MAPK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5657713 | 0.76 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1ATMHPGD | |
| SCHEMBL5166737 | 0.76 | L3MBTL1 (0.45) | L3MBTL1MAPTNPSR1ATMHPGD | |
| SCHEMBL8045970 | 0.75 | L3MBTL1 (0.56) | L3MBTL1MAPTNPSR1ATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018200-A1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |