Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164811 | 0.80 | GAA (0.55) | KDM4EMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL13370774 | 0.76 | HTR6 (0.58) | KDM4EHTR6KMT2AGLATP53 | |
| SCHEMBL9390366 | 0.76 | L3MBTL1 (0.47) | L3MBTL1KDM4EMAPTATMHPGD | |
| SCHEMBL28835130 | 0.76 | ALDH1A1 (0.50) | L3MBTL1KDM4EHTR6KMT2ASMN1; SMN2 | |
| SCHEMBL8714605 | 0.75 | HTR6 (0.50) | L3MBTL1KDM4EMAPTATMHPGD | |
| SCHEMBL5420692 | 0.74 | L3MBTL1 (0.71) | L3MBTL1KDM4EMAPTATMHPGD | |
| SCHEMBL4247206 | 0.72 | HTR6 (0.58) | KDM4EHTR6KMT2ATP53SMN1; SMN2 | |
| SCHEMBL5164020 | 0.72 | TSHR (0.41) | KDM4EMAPTHPGDHTR6GLA | |
| SCHEMBL20314686 | 0.72 | HTR6 (0.50) | HTR6 | |
| 1-Methoxy-2-Propoxybenzene SCHEMBL791386 | 0.72 | L3MBTL1 (0.60) | L3MBTL1MAPTHPGDTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765332-A2 | TRISUBSTITUTED NITROGEN MODULATORS OF TYROSINE PHOSPHATASES | Cengent Therapeutics, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006009876-A2 | TRISUBSTITUTED NITROGEN MODULATORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-01-26 | — | — | WO | disclosed |