Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 3/20 | 0.36 |
| ▸ | TK2 | O00142 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386928 | 0.77 | PKM (0.38) | KMT2A | |
| SCHEMBL6911384 | 0.75 | TYMP (0.44) | TK1MAPK1HPGDTYMP | |
| SCHEMBL11257611 | 0.74 | TK1 (0.49) | TK1MAPK1HPGDCYP1A2CYP2C19 | |
| SCHEMBL4342113 | 0.73 | TYMP (0.49) | TK1MAPK1HPGDTYMP | |
| SCHEMBL13261412 | 0.70 | TK1 (0.62) | TK1MAPK1HPGDCYP1A2CYP2C19 | |
| SCHEMBL6890252 | 0.69 | TK1 (0.65) | TK1MAPK1HPGDCYP1A2CYP2C19 | |
| SCHEMBL18226895 | 0.69 | TK1 (0.65) | TK1MAPK1HPGDCYP1A2CYP2C19 | |
| SCHEMBL6883307 | 0.69 | TK1 (0.65) | TK1MAPK1HPGDCYP1A2CYP2C19 | |
| SCHEMBL10337895 | 0.69 | TK1 (0.65) | TK1MAPK1HPGDCYP1A2CYP2C19 | |
| SCHEMBL3436939 | 0.66 | TYMP (0.45) | TK1MAPK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000473-A2 | PENTAVALENT SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING STEREOSPECIFIC ALKYLPHOSPHONATES AND ARYLPHOSPHONATES | RES CORP TECHNOLOGIES INC (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1994000472-A2 | TRIVALENT SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING STEREOSPECIFIC ALKYLPHOSPHONATES AND ARYLPHOSPHONATES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-01-06 | — | — | WO | disclosed |