Diethylamine

Diethylamine

SCHEMBL93913

C=Cc1ccc(CC)cc1.CCNCC

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CCKAR

The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HDAC8 Q9BY41 1/20 0.40
MAOA P21397 1/20 0.39
ALOX5 P09917 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
THRB P10828 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
CYP2C9 P11712 1/20 0.36
IGF1R P08069 1/20 0.36
PIM1 P11309 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
TUBB1 Q9H4B7 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15915 0.89 ALDH1A1 (0.58) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
Dimethylamine SCHEMBL10633923 0.87 ALDH1A1 (0.50) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
Ethylene SCHEMBL28003592 0.87 ALDH1A1 (0.55) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
Arsenic SCHEMBL28835563 0.87 ALDH1A1 (0.55) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
SCHEMBL3280867 0.83 ALDH1A1 (0.46) ALDH1A1LMNAMAPTSMN1; SMN2HDAC8
SCHEMBL4526640 0.83 ALDH1A1 (0.50) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
Diethylamine SCHEMBL94063 0.81 ALDH1A1 (0.48) ALDH1A1MAPTSMN1; SMN2HDAC8TAS1R3
SCHEMBL5585065 0.81 ALDH1A1 (0.48) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
Styrene SCHEMBL9795236 0.81 ALDH1A1 (0.61) ALDH1A1LMNAMAPTHPGDSMN1; SMN2
SCHEMBL8975771 0.81 ALDH1A1 (0.48) ALDH1A1LMNAMAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240101807-A1 FLAME RETARDANT COMPOSITION FOR FOAMED STYRENE RESIN, FLAME-RETARDANT FOAMED STYRENE-BASED RESIN COMPOSITION, AND EXTRUSION FOAM-MOLDED PRODUCT OF SAME DKS CO. LTD. (JP) 2024-03-28 US disclosed
EP-4289896-A1 FLAME RETARDANT COMPOSITION FOR FOAMED STYRENE RESIN, FLAME-RETARDANT FOAMED STYRENE-BASED RESIN COMPOSITION, AND EXTRUSION FOAM-MOLDED PRODUCT OF SAME DKS Co. Ltd. (JP) 2023-12-13 EP disclosed
US-20230089518-A1 FLAME RETARDANT COMPOSITION FOR FOAMED STYRENE RESIN, FLAME-RETARDANT FOAMED-STYRENE-BASED RESIN COMPOSITION, AND EXTRUDED FOAM MOLDED PRODUCT THEREOF DKS CO. LTD. (JP) 2023-03-23 US disclosed
EP-4119635-A1 FLAME RETARDANT COMPOSITION FOR FOAMED STYRENE RESIN, FLAME-RETARDANT FOAMED-STYRENE-BASED RESIN COMPOSITION, AND EXTRUDED FOAM MOLDED PRODUCT THEREOF DKS Co. Ltd. (JP) 2023-01-18 EP disclosed
WO-2022168564-A1 FLAME RETARDANT COMPOSITION FOR FOAMED STYRENE RESIN, FLAME-RETARDANT FOAMED STYRENE-BASED RESIN COMPOSITION, AND EXTRUSION FOAM-MOLDED PRODUCT OF SAME 第一工業製薬株式会社 2022-08-11 WO disclosed
US-11185851-B2 Polymer-supported metal TAKASAGO INTERNATIONAL CORPORATION (JP) 2021-11-30 US disclosed
EP-3670585-A1 FLAME-RESISTANT FOAMED STYRENE-BASED RESIN COMPOSITION Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2020-06-24 EP disclosed
US-10633502-B2 Flame-retardant foamable styrene resin composition DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2020-04-28 US disclosed
EP-2921520-B1 FLAME-RETARDANT FOAMED STYRENE RESIN COMPOSITION DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2020-02-05 EP disclosed
EP-3417939-A1 METAL-SUPPORTED MACROMOLECULE Takasago International Corporation (JP) 2018-12-26 EP disclosed
EP-2921520-A1 FLAME-RETARDANT FOAMED STYRENE RESIN COMPOSITION Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2015-09-23 EP disclosed
EP-2426152-B1 FLAME-RETARDANT EXPANDABLE STYRENE RESIN PARTICLES AND METHOD FOR PRODUCING SAME DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2014-06-04 EP disclosed
EP-1983028-B1 FLAME-RETARDANT STYRENE RESIN COMPOSITION DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2012-08-15 EP disclosed
EP-2426152-A1 FLAME-RETARDANT EXPANDABLE STYRENE RESIN PARTICLES AND METHOD FOR PRODUCING SAME Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2012-03-07 EP disclosed
EP-2426165-A1 FLAME-RETARDANT EXPANDABLE STYRENE RESIN COMPOSITION Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2012-03-07 EP disclosed
US-20110319507-A1 FLAME-RETARDED FOAMABLE STYRENE-BASED RESIN BEADS AND PROCESS FOR PRODUCING THE SAME DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2011-12-29 US disclosed
US-20100168263-A1 FLAME-RETARDED STYRENE-BASED RESIN COMPOSITIONS DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2010-07-01 US disclosed
EP-1983028-A1 FLAME-RETARDANT STYRENE RESIN COMPOSITION Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2008-10-22 EP disclosed
US-4721666-A Photographic element FUJI PHOTO FILM CO., LTD. (JP) 1988-01-26 US disclosed
US-4596756-A Ethylenically unsaturated monomer, unsaturated nitrile containing monomer FUJI PHOTO FILM CO., LTD. (JP) 1986-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185851-B2 Polymer-supported metal SOD1, PCNA, MAX ALDH1A1 4117/4885LMNA 4342/4885MAPT 906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.