Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 4/20 | 0.41 |
| ▸ | DDO | Q99489 | 3/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393317 | 0.88 | FASN (0.57) | FASNARCA1CA2DAO | |
| SCHEMBL3396789 | 0.81 | DAO (0.63) | FASNNOS3NOS1NOS2DAO | |
| SCHEMBL9387738 | 0.79 | DAO (0.65) | DAODDO | |
| SCHEMBL9007832 | 0.76 | DAO (0.65) | DAODDO | |
| SCHEMBL9007836 | 0.76 | METAP2 (0.49) | DAODDO | |
| SCHEMBL7350621 | 0.76 | DAO (0.65) | DAO | |
| SCHEMBL3363129 | 0.75 | DAO (0.54) | FASNDAODDO | |
| SCHEMBL3422876 | 0.75 | DAO (0.54) | FASNDAODDO | |
| SCHEMBL25246466 | 0.74 | PARP1 (0.56) | FASNNOS3NOS1NOS2CA1 | |
| SCHEMBL9393132 | 0.74 | GRIN2D (0.38) | FASNDAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |