Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 7/20 | 0.54 |
| ▸ | FASN | P49327 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363129 | 0.81 | DAO (0.54) | DAOFASNSRCDDOGRIN2D | |
| SCHEMBL3359995 | 0.79 | DAO (0.58) | DAOSRCDDOGRIN2DGRIN3B | |
| SCHEMBL3360786 | 0.76 | DAO (0.58) | DAOSRCDDOGRIN2DGRIN3B | |
| SCHEMBL9392647 | 0.75 | FASN (0.47) | DAOFASNDDO | |
| SCHEMBL3396789 | 0.71 | DAO (0.63) | DAOFASNDDO | |
| SCHEMBL3422279 | 0.71 | DAO (0.61) | DAOFASNDDO | |
| SCHEMBL9393132 | 0.71 | GRIN2D (0.38) | DAOFASNDDOGRIN2DGRIN3B | |
| SCHEMBL16767849 | 0.70 | DAO (1.00) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8873379 | 0.69 | GRIN1 (0.51) | DAOSRCGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9393317 | 0.69 | FASN (0.57) | DAOFASNDDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |