SCHEMBL939341

SCHEMBL939341

O=C(CC(=O)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
PLOD2 O00469 3/20 0.36
PLOD3 O60568 2/20 0.35
PLOD1 Q02809 2/20 0.35
HDAC6 Q9UBN7 1/20 0.34
FAAH O00519 8/20 0.33
CES1 P23141 6/20 0.32
CES2 O00748 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP1A2 P05177 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15271614 0.93 THRB (0.46) THRBPLOD2PLOD3PLOD1HDAC6
SCHEMBL2221105 0.92 THRB (0.42) THRBCA2
SCHEMBL2891773 0.84 PLOD2 (0.39) PLOD2PLOD3PLOD1HDAC6FAAH
SCHEMBL412034 0.82 THRB (0.56) THRBCA2
SCHEMBL11834156 0.82 THRB (0.56) THRBCA2
SCHEMBL27737984 0.82 PLOD2 (0.38) PLOD2PLOD3PLOD1HDAC6FAAH
SCHEMBL20453952 0.81 THRB (0.34) THRBCA2
SCHEMBL26493732 0.81 THRB (0.34) THRBCA2
SCHEMBL196683 0.81 THRB (0.34) THRBCA2
SCHEMBL183178 0.81 PLOD2 (0.46) PLOD2PLOD3PLOD1HDAC6FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7485611-B2 Supercritical fluid-based cleaning compositions and methods ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2009-02-03 US claimed
US-20070149429-A9 SUPERCRITICAL FLUID-BASED CLEANING COMPOSITIONS AND METHODS POCO GRAPHITE, INC. 2007-06-28 US claimed
US-20040224865-A1 SUPERCRITICAL FLUID-BASED CLEANING COMPOSITIONS AND METHODS ADVANCED TECHNOLOGY MATERIALS, INC. 2004-11-11 US claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
US-20030099424-A1 Optical gain media and methods for making and using same MOHAJER YOUSEF (US) 2003-05-29 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
EP-0507074-B1 Cleaning agents comprising beta-diketone and beta-ketoimine ligands and a process for using the same AIR PROD & CHEM (US) 1996-01-03 EP claimed
US-5221366-A Oxidizing metal to metal oxide thin film, complexing and sublimation of metal-ligand complex from the surface AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-06-22 US claimed
EP-0507074-A1 Cleaning agents comprising beta-diketone and beta-ketoimine ligands and a process for using the same AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-10-07 EP claimed
US-5141549-A Method of fabricating rare earth doped planar optical waveguide for integrated optical circuit THE CHARLES STARK DRAPER LABORATORIES (US) 1992-08-25 US claimed
US-5094701-A Cleaning agents comprising beta-diketone and beta-ketoimine ligands and a process for using the same AIR PRODUCTS AND CHEMICALS, INC. (US) 1992-03-10 US claimed
US-5062902-A Fluxing agents comprising β-diketone and β-ketoimine ligands and a process for using the same AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-11-05 US claimed
US-5009725-A Removal of surface oxides by forming metal-ligand complex; sublimination AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-04-23 US claimed
US-4960466-A FORMING CADMIUM STANNATE IN PRESENCE OF BETA-DIKETONE AND NITROGEN COMPOUND, SUCH AS AMINE OR AMMONIA; HIGH ELECTRO-CONDUCTIVITY VICTORIAN SOLAR ENERGY COUNCIL (AU) 1990-10-02 US claimed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
US-4206132-A Lanthanide chelate of a fluorinated ligand THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1980-06-03 US disclosed
US-4180386-A ANTIKNOCK FUEL ADDITIVES E. I. DU PONT DE NEMOURS & COMPANY (US) 1979-12-25 US disclosed