Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA8 | P11142 | 4/20 | 0.59 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393748 | 1.00 | HSPA8 (0.59) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL9395442 | 0.89 | HSPA8 (0.49) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL9395437 | 0.89 | HSPA8 (0.49) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL9394617 | 0.81 | ADORA3 (0.59) | GAPDHADORA3SMN1; SMN2ADORA2ASLC28A2 | |
| SCHEMBL9393755 | 0.81 | ADORA3 (0.59) | GAPDHADORA3SMN1; SMN2ADORA2ASLC28A2 | |
| SCHEMBL9394656 | 0.81 | HSPA8 (0.60) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL9394663 | 0.81 | HSPA8 (0.60) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL9394731 | 0.80 | HSPA8 (0.59) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL9394722 | 0.80 | HSPA8 (0.59) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL9394744 | 0.80 | HSPA8 (0.59) | HSPA8HSPA5RXFP1GAPDHHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365849-B1 | Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives | MERRELL DOW PHARMA (US) | 1994-09-14 | — | — | EP | disclosed |
| EP-0365849-A2 | Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-05-02 | — | — | EP | disclosed |