SCHEMBL9393755

SCHEMBL9393755

C=C=C1[C@H](n2cnc3c(N)ncnc32)O[C@H](CO)[C@H]1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 4/20 0.59
▸ ADORA2A P29274 2/20 0.58
▸ PI4KA P42356 2/20 0.58
▸ PI4K2B Q8TCG2 2/20 0.58
▸ PI4K2A Q9BTU6 2/20 0.58
▸ PI4KB Q9UBF8 2/20 0.58
▸ ADORA1 P30542 2/20 0.58
▸ DPP4 P27487 1/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ SLC28A1 O00337 1/20 0.58
▸ MAP3K7 O43318 1/20 0.58
▸ SLC28A2 O43868 1/20 0.58
▸ GAPDH P04406 1/20 0.58
▸ MAPK1 P28482 1/20 0.58
▸ ADORA2B P29275 1/20 0.58
▸ STAT6 P42226 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.58
▸ DOT1L Q8TEK3 1/20 0.58
▸ SLC29A1 Q99808 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9394617 1.00 ADORA3 (0.59) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL8807365 0.85 ADORA3 (0.62) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL8807358 0.85 ADORA3 (0.62) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL9394671 0.85 ADORA3 (0.51) ADORA3ADORA2AADORA1MAPK1ADORA2B
SCHEMBL9397387 0.85 LMNA (0.47) ADORA3ADORA2AADORA1MAPK1SMN1; SMN2
SCHEMBL9397406 0.85 LMNA (0.47) ADORA3ADORA2AADORA1MAPK1SMN1; SMN2
SCHEMBL9394665 0.85 ADORA3 (0.51) ADORA3ADORA2AADORA1MAPK1ADORA2B
SCHEMBL30870546 0.83 ADORA3 (0.62) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL9393756 0.81 HSPA8 (0.59) ADORA3ADORA2ASLC28A2GAPDHSMN1; SMN2
SCHEMBL9393748 0.81 HSPA8 (0.59) ADORA3ADORA2ASLC28A2GAPDHSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102421914-A Molecular detection based on abortive transcription RIBOMED BIOTECHNOLOGIES INC 2012-04-18 — — CN claimed
EP-0365849-B1 Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives MERRELL DOW PHARMA (US) 1994-09-14 — — EP claimed
EP-0365849-A2 Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1990-05-02 — — EP claimed
CN-117343990-B Method and kit for determining target polynucleotide and probe set 牛津纳米孔科技公开有限公司 2025-05-30 — — CN disclosed
CN-118957041-A Method for determining polymer sequences 牛津纳米孔科技公开有限公司 2024-11-15 — — CN disclosed
CN-112703256-B Method for determining polymer sequences 牛津纳米孔科技公开有限公司 2024-09-03 — — CN disclosed
CN-117343990-A Method and kit for determining target polynucleotide and probe set 牛津纳米孔科技公开有限公司 2024-01-05 — — CN disclosed
CN-105916873-B Efficient synthesis of long RNAs using the reverse method 坎姆根公司 2020-06-19 — — CN disclosed
CN-102439025-B RNA synthesizes-is used for inverse composition RNA phosphoramidite, and synthesizes in 3 ' ends the application in RNA the facilitating the introduction of of part, chromophore and trim 坎姆根公司 2017-08-01 — — CN disclosed
CN-106232834-A Sample preparation methods 牛津纳米孔技术公司 2016-12-14 — — CN disclosed
CN-105916873-A Efficient synthesis of long RNAs using the reverse method 坎姆根公司 2016-08-31 — — CN disclosed
CN-105916872-A Dithiolane functionalized nucleoside imides and supports for more robust immobilization of biomolecules on solid surfaces 坎姆根公司 2016-08-31 — — CN disclosed
CN-102421914-A Molecular detection based on abortive transcription RIBOMED BIOTECHNOLOGIES INC 2012-04-18 — — CN disclosed
EP-0365849-B1 Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives MERRELL DOW PHARMA (US) 1994-09-14 — — EP disclosed
EP-0365849-A2 Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1990-05-02 — — EP disclosed
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