Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423793 | 0.85 | MEN1 (0.53) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9394554 | 0.80 | MAPT (0.45) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9423418 | 0.75 | MEN1 (0.45) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9423796 | 0.73 | KMT2A (0.41) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9423257 | 0.73 | PTGER1 (0.51) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9392440 | 0.68 | MAPT (0.42) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9074132 | 0.68 | MEN1 (0.63) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6643390 | 0.67 | SRD5A1 (0.46) | MEN1KMT2AALDH1A1MAPTALOX15 | |
| SCHEMBL9135541 | 0.67 | MEN1 (0.54) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8885341 | 0.67 | PTGER1 (0.68) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027981-A1 | SQUARIC ACID DERIVATIVES OF DIBENZOXAZEPINS OR DIBENZOTHIAZEPINES USEFUL AS ANALGESICS | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |
| US-5354746-A | Prostaglandin inhibitor, analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | claimed |
| US-5354746-A | Prostaglandin inhibitor, analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | disclosed |