Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392440 | 0.90 | MAPT (0.42) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9277049 | 0.83 | PTGER1 (0.49) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9394554 | 0.77 | MAPT (0.45) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9423793 | 0.75 | MEN1 (0.53) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9393942 | 0.73 | MEN1 (0.46) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9393936 | 0.71 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9273057 | 0.65 | MEN1 (0.57) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9423418 | 0.65 | MEN1 (0.45) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9272255 | 0.65 | PTGER1 (0.54) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8885341 | 0.64 | PTGER1 (0.68) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354746-A | Prostaglandin inhibitor, analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | claimed |
| US-5354746-A | Prostaglandin inhibitor, analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | disclosed |