Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423796 | 0.90 | KMT2A (0.41) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9423793 | 0.80 | MEN1 (0.53) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9394554 | 0.76 | MAPT (0.45) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9277049 | 0.71 | PTGER1 (0.49) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9273057 | 0.69 | MEN1 (0.57) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9393942 | 0.68 | MEN1 (0.46) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6969652 | 0.67 | MEN1 (0.69) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL676665 | 0.67 | MEN1 (0.69) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| Hydrazine SCHEMBL11827760 | 0.65 | MEN1 (0.66) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9423418 | 0.65 | MEN1 (0.45) | MAPTMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027981-A1 | SQUARIC ACID DERIVATIVES OF DIBENZOXAZEPINS OR DIBENZOTHIAZEPINES USEFUL AS ANALGESICS | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | claimed |