Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23700156 | 0.78 | EPHX1 (0.39) | TRPM8TRPA1EPHX1 | |
| SCHEMBL23700155 | 0.78 | EPHX1 (0.39) | TRPM8TRPA1EPHX1 | |
| SCHEMBL10713470 | 0.77 | TRPM8 (0.46) | TRPM8TRPA1EPHX1ALDH1A1OPRM1 | |
| SCHEMBL21380222 | 0.75 | EPHX1 (0.43) | TRPM8TRPA1EPHX1KCNA5 | |
| SCHEMBL29136141 | 0.75 | EPHX1 (0.45) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL7771618 | 0.75 | TRPM8 (0.40) | TRPM8TRPA1EPHX1ALDH1A1OPRM1 | |
| SCHEMBL11215068 | 0.74 | TRPM8 (0.42) | TRPM8TRPA1EPHX1ALDH1A1OPRM1 | |
| SCHEMBL5114601 | 0.71 | TRPM8 (0.42) | TRPM8TRPA1EPHX1ALDH1A1OPRM1 | |
| SCHEMBL5114606 | 0.71 | TRPM8 (0.46) | TRPM8TRPA1EPHX1ALDH1A1OPRM1 | |
| SCHEMBL2407691 | 0.71 | TRPM8 (0.42) | TRPM8TRPA1EPHX1ALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994028872-A1 | NON-ALCOHOLIC COLD AND SINUS MEDICATION | WARNER-LAMBERT COMPANY (US) | 1994-12-22 | — | — | WO | disclosed |