Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394027 | 0.83 | CCR1 (0.40) | ALDH1A1SLC6A4IDO1TDO2CCR1 | |
| SCHEMBL1095213 | 0.76 | ALDH1A1 (0.45) | ALDH1A1GAALMNAPOLBMAPT | |
| SCHEMBL1097210 | 0.75 | USP2 (0.44) | ALDH1A1GAALMNAPOLBTP53 | |
| Benzene SCHEMBL1097123 | 0.73 | USP2 (0.42) | ALDH1A1GAALMNAPOLBMAPT | |
| SCHEMBL10994456 | 0.72 | ALDH1A1 (0.45) | ALDH1A1GAALMNAPOLBMAPT | |
| SCHEMBL8925358 | 0.72 | GGPS1 (0.39) | ALDH1A1GAALMNAPOLBMAPT | |
| SCHEMBL8925354 | 0.72 | ALDH1A1 (0.35) | ALDH1A1GAALMNAPOLBMAPT | |
| SCHEMBL11861718 | 0.70 | ALDH1A1 (0.43) | ALDH1A1GAALMNAPOLBMAPT | |
| SCHEMBL11857458 | 0.70 | LMNA (0.49) | ALDH1A1GAALMNAPOLBMAPT | |
| SCHEMBL11862705 | 0.70 | ESR1 (0.48) | ALDH1A1GAALMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994019363-A1 | PROCESS FOR PREPARING PHOSPHOROTHIOATE OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1994-09-01 | — | — | WO | disclosed |