Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731834 | 0.78 | AKR1C1 (0.37) | HDAC4MEN1KMT2AMAPTAKR1B1 | |
| SCHEMBL14471899 | 0.77 | HDAC4 (0.41) | CYP11B1HDAC4 | |
| SCHEMBL8424787 | 0.77 | TSHR (0.38) | TSHRERCC5FEN1NOTUMALDH1A1 | |
| SCHEMBL28755670 | 0.76 | HDAC4 (0.39) | CYP11B1HDAC4P2RX7 | |
| SCHEMBL4451679 | 0.73 | HDAC4 (0.41) | HDAC4KMT2ALMNA | |
| Benzene SCHEMBL28354853 | 0.73 | HDAC4 (0.41) | HDAC4KMT2ALMNA | |
| SCHEMBL29265482 | 0.70 | KMT2A (0.37) | TSHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28447402 | 0.70 | EGLN1 (0.39) | CYP11B1ALDH1A1 | |
| SCHEMBL9458297 | 0.67 | APP (0.33) | AKR1B1 | |
| SCHEMBL29120630 | 0.67 | HDAC4 (0.39) | CYP11B1HDAC4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994028422-A1 | A POLYCHLORINATED BIPHENYLS (PCB) IMMUNOASSAY METHOD, ITS COMPONENTS AND A KIT FOR USE IN PERFORMING THE SAME | ENSYS ENVIRONMENTAL PRODUCTS INC. (US) | 1994-12-08 | — | — | WO | disclosed |