SCHEMBL9395656

SCHEMBL9395656

CC(=O)[CH]C(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TDP1 Q9NUW8 2/20 0.56
MAPK1 P28482 2/20 0.56
AKT1 P31749 2/20 0.54
NFE2L2 Q16236 1/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
RECQL P46063 2/20 0.50
MAPT P10636 5/20 0.48
PLIN1 O60240 2/20 0.48
LMNA P02545 2/20 0.48
PLIN5 Q00G26 2/20 0.48
ABHD5 Q8WTS1 2/20 0.48
BCHE P06276 1/20 0.48
TNFRSF1A P19438 1/20 0.48
ACHE P22303 1/20 0.48
MAOB P27338 1/20 0.48
CYP1B1 Q16678 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7147542 0.85 ALDH1A1 (0.67) ALDH1A1TDP1MAPK1AKT1NFE2L2
SCHEMBL27665282 0.82 ALDH1A1 (0.64) ALDH1A1TDP1MAPK1AKT1NFE2L2
SCHEMBL28231204 0.82 AKT1 (0.56) ALDH1A1TDP1MAPK1AKT1NFE2L2
SCHEMBL9478107 0.80 ALDH1A1 (0.61) ALDH1A1TDP1MAPK1AKT1NFE2L2
SCHEMBL3887709 0.79 RECQL (0.59) ALDH1A1TDP1MAPK1AKT1NFE2L2
SCHEMBL280061 0.79 NFE2L2 (0.61) ALDH1A1TDP1MAPK1AKT1NFE2L2
SCHEMBL3265780 0.77 MAPT (0.53) ALDH1A1TDP1MEN1KMT2ACES2
SCHEMBL10984963 0.76 NFE2L2 (0.64) ALDH1A1TDP1MAPK1AKT1NFE2L2
SCHEMBL566675 0.76 NFE2L2 (0.64) ALDH1A1TDP1MAPK1AKT1NFE2L2
SCHEMBL10984957 0.76 NFE2L2 (0.64) ALDH1A1TDP1MAPK1AKT1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591217-B Preparation method of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane and lactone intermediate thereof 浙江新和成股份有限公司 2024-04-16 CN claimed
CN-115043772-B Preparation method of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane 浙江新和成股份有限公司 2024-03-15 CN claimed
CN-114591217-A Process for the preparation of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane and lactone intermediates thereof 浙江新和成股份有限公司 2022-06-07 CN claimed
EP-0417555-B1 Pentamethine dyes and derivatives BAYER AG (DE) 1993-11-03 EP claimed
US-5118814-A Pressure sensitive and heat sensitive recording media BAYER AKTIENGESELLSCHAFT (DE) 1992-06-02 US claimed
EP-0370198-A1 Tetraindolyl heptamethine derivatives BAYER AG (DE) 1990-05-30 EP claimed
CN-114591217-B Preparation method of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane and lactone intermediate thereof 浙江新和成股份有限公司 2024-04-16 CN disclosed
CN-115043772-B Preparation method of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane 浙江新和成股份有限公司 2024-03-15 CN disclosed
CN-115043772-A Preparation method of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane 浙江新和成股份有限公司 2022-09-13 CN disclosed
CN-114591217-A Process for the preparation of 6, 6-dimethyl-3-azabicyclo- [3.1.0] -hexane and lactone intermediates thereof 浙江新和成股份有限公司 2022-06-07 CN disclosed
CN-113652672-A Synthesis and use of precursors for ALD of molybdenum-or tungsten-containing thin films ASM IP 控股有限公司 2021-11-16 CN disclosed
CN-107923039-B Synthesis and use of precursors for ALD of molybdenum-or tungsten-containing thin films ASM IP 控股有限公司 2021-06-29 CN disclosed
CN-107148341-B Multilayer structure, method for producing same, packaging material and product obtained using same, and protective sheet for electronic device 株式会社可乐丽 2020-06-16 CN disclosed
US-4958021-A PRESSURE AND HEAT SENSITIVE RECORDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 1990-09-18 US disclosed
EP-0370198-A1 Tetraindolyl heptamethine derivatives BAYER AG (DE) 1990-05-30 EP disclosed
US-4841050-A Carbazole containing benzopyrans BASF AKTIENGESELLSCHAFT (DE) 1989-06-20 US disclosed
EP-0236973-B1 BENZOPYRANES AND THEIR USE IN A RECORDING SYSTEM BASF Aktiengesellschaft (DE) 1989-06-14 EP disclosed
EP-0304613-A1 Benzopyran derivatives BASF Aktiengesellschaft (DE) 1989-03-01 EP disclosed
EP-0236973-A2 Benzopyranes and their use in a recording system BASF Aktiengesellschaft (DE) 1987-09-16 EP disclosed
US-4022773-A 7-ACYLAMINO-3-SUBSTITUTED-3-CEPHEM-4-CARBOXYLIC ACIDS, 1-OXIDES ISHIMARU TOSHIYASU 1977-05-10 US disclosed