Benzotript

Benzotript

SCHEMBL93960

O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ITGB2 P05107 9/20 0.73
ICAM1 P05362 9/20 0.73
ITGAL P20701 9/20 0.73
ERAP2 Q6P179 1/20 0.72
TACR1 P25103 2/20 0.72
UBASH3B Q8TF42 1/20 0.71
PPARG P37231 1/20 0.69
CCKBR P32239 1/20 0.67
CA12 O43570 1/20 0.64
CA1 P00915 1/20 0.64
CA9 Q16790 1/20 0.64
BBOX1 O75936 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzotript SCHEMBL9818252 1.00 ITGB2 (0.73) ITGB2ICAM1ITGALERAP2TACR1
SCHEMBL9466705 0.92 ITGB2 (0.78) ITGB2ICAM1ITGALERAP2TACR1
SCHEMBL30616778 0.92 ITGB2 (0.78) ITGB2ICAM1ITGALERAP2TACR1
SCHEMBL5259129 0.92 ITGB2 (0.78) ITGB2ICAM1ITGALERAP2TACR1
SCHEMBL5191302 0.92 ITGB2 (0.78) ITGB2ICAM1ITGALERAP2TACR1
SCHEMBL11870861 0.91 ERAP2 (0.76) ITGB2ICAM1ITGALERAP2CA12
SCHEMBL22206878 0.90 ITGB2 (0.77) ITGB2ICAM1ITGALERAP2TACR1
SCHEMBL22206876 0.90 ITGB2 (0.77) ITGB2ICAM1ITGALERAP2TACR1
SCHEMBL9828342 0.89 ERAP2 (0.74) ITGB2ICAM1ITGALERAP2TACR1
SCHEMBL9828348 0.89 ERAP2 (0.74) ITGB2ICAM1ITGALERAP2TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023017856-A1 MIXED POWDER, METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENT ELEMENT THAT USES MIXED POWDER, AND VAPOR DEPOSITION COMPOSITION 出光興産株式会社 2023-02-16 WO claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
JP-2011528275-A 2011-11-17 JP claimed
EP-2313122-A1 DRUG DELIVERY MEDICAL DEVICE Micell Technologies, Inc. (US) 2011-04-27 EP claimed
US-20100286073-A1 COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE GENERICS (UK) LIMITED (GB) 2010-11-11 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-2205229-A1 COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE Mintails Limited (CY) 2010-07-14 EP claimed
WO-2010009335-A1 DRUG DELIVERY MEDICAL DEVICE MICELL TECHNOLOGIES, INC. (US) 2010-01-21 WO claimed
WO-2009044202-A1 COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE MINTAILS LIMITED (CY) 2009-04-09 WO claimed
US-20090054369-A1 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS, INC. (US) 2009-02-26 US claimed
WO-2007019221-A2 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS, INC. (US) 2007-02-15 WO claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
WO-1995028081-A1 ADDRESSING BAIT AVERSION BY DISRUPTING ASSOCIATIVE LEARNING THE MEAT INDUSTRY RESEARCH INSTITUTE OF NEW ZEALAND INC. (NZ) 1995-10-26 WO claimed
WO-1995021622-A1 GEL-FORMING POLYPEPTIDE DERIVATIVES BRIGHAM & WOMEN'S HOSPITAL (US) 1995-08-17 WO claimed
WO-1995021380-A1 ASSAY FOR SCREENING OF RECEPTOR ANTAGONISTS LUDWIG INSTITUTE FOR CANCER RESEARCH (US) 1995-08-10 WO claimed
EP-0393575-B1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent SEARLE & CO (US) 1994-03-16 EP claimed
EP-0422181-A1 METHOD AND MEANS FOR INDUCING, RESP., PREVENTING CONSTRICTION OF THE PUPIL IN THE EYE Kabi Pharmacia AB (SE) 1991-04-17 EP claimed
EP-0393575-A1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent G.D. Searle & Co. (US) 1990-10-24 EP claimed
WO-1990011773-A1 METHOD AND MEANS FOR INDUCING, RESP., PREVENTING CONSTRICTION OF THE PUPIL IN THE EYE PHARMACIA AB (SE) 1990-10-18 WO claimed
US-4000297-A GASTROENTERIC ACTIVITY ROTTA RESEARCH LABORATORIUM S.P.A. (IT) 1976-12-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054369-A1 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS SI, SLC29A2, SLC29A1 ITGB2 1873/4885ICAM1 1759/4885ITGAL 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.