Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17693473 | 0.94 | ZDHHC20 (0.39) | ZDHHC20ZDHHC2TSHRHPGD | |
| SCHEMBL9396076 | 0.92 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TSHRHPGDCA12 | |
| SCHEMBL17689797 | 0.92 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TSHRHPGDCA12 | |
| SCHEMBL9398097 | 0.92 | ZDHHC20 (0.52) | ZDHHC20ZDHHC2TSHRHPGDCA12 | |
| SCHEMBL12302189 | 0.88 | ZDHHC20 (0.35) | ZDHHC20ZDHHC2 | |
| SCHEMBL17689808 | 0.84 | ZDHHC20 (0.39) | ZDHHC20ZDHHC2TSHRHPGD | |
| SCHEMBL3889351 | 0.84 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRHPGDMAPK1 | |
| SCHEMBL15267170 | 0.81 | ZDHHC20 (0.43) | ZDHHC20ZDHHC2TSHRHPGDCA12 | |
| SCHEMBL13609159 | 0.81 | ZDHHC20 (0.40) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL9398065 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387706-B1 | Oxygen permeable hard contact lens | KURARAY CO (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5162391-A | Copolymer of Siloxanyalkylacrylamide of a Fluoro Monomer | KURARAY CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0387706-A2 | Oxygen permeable hard contact lens | KURARAY CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |