Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15655347 | 0.95 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2TSHRHPGD | |
| SCHEMBL9764016 | 0.84 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2 | |
| SCHEMBL9396171 | 0.84 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL15655992 | 0.83 | P2RX4 (0.34) | ZDHHC20ZDHHC2HPGD | |
| SCHEMBL13609159 | 0.82 | ZDHHC20 (0.40) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL2046249 | 0.81 | ZDHHC20 (0.32) | ZDHHC20ZDHHC2 | |
| SCHEMBL28036839 | 0.81 | CA12 (0.34) | TSHRMAPK1HPGDALDH1A1CA12 | |
| SCHEMBL23421037 | 0.80 | ZDHHC20 (0.54) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL19610469 | 0.80 | ZDHHC20 (0.59) | ZDHHC20ZDHHC2TSHRMAPK1APP | |
| SCHEMBL4316811 | 0.79 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7621966-B2 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2009-11-24 | — | — | US | disclosed |
| US-7621966-B2 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2009-11-24 | — | — | US | disclosed |
| EP-2065026-A1 | Composition comprising, in an anhydrous cosmetically acceptable medium, electrophilic monomers and an acid, and its use for cosmetic treatment of hair | L'Oreal (FR) | 2009-06-03 | — | — | EP | disclosed |
| US-20080038218-A1 | Cosmetic composition comprising at least one electrophilic monomer, at least one fluoro compound and at least one liquid organic solvent | L'OREAL S.A. (FR) | 2008-02-14 | — | — | US | disclosed |
| US-20080038218-A1 | Cosmetic composition comprising at least one electrophilic monomer, at least one fluoro compound and at least one liquid organic solvent | L'OREAL S.A. (FR) | 2008-02-14 | — | — | US | disclosed |
| WO-2007125236-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE ELECTROPHILIC MONOMER AND AT LEAST ONE CROSS-LINKED ELASTOMER ORGANOPOLYSILOXANE | L'OREAL (FR) | 2007-11-08 | — | — | WO | disclosed |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
| US-20070251027-A1 | Dyeing composition comprising at least one soluble fluorescent compound, at least one electrophilic monomer and at least one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
| US-20070251027-A1 | Dyeing composition comprising at least one soluble fluorescent compound, at least one electrophilic monomer and at least one liquid organic solvent | L'OREAL S.A. (FR) | 2007-11-01 | — | — | US | disclosed |
| EP-1647264-A1 | use for cosmetic treatment of keratinic material of a composition comprising an electrophilic monomer and a non-siloxane polymer, thereby achieving a rigid coating | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1647265-A1 | Use for the cosmetic treatment of keratinous material of non sticky compositions based on electrophilic monomeres and non-silicon polymers | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1647260-A1 | use for cosmetic treatment of keratinic material of a composition comprising an electrophilic monomer and a non-siloxane polymer, thereby achieving a soft coating | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1647259-A1 | use for treatment of keratinic materials of compositions comprising electrophilic monomers and agents forming liquid crystals | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1647258-A1 | Hair care composition based on electrophilic monomers and lubricating solid micro or nano particles | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1647308-A1 | Use of a composition baded on electrophilic monomers and micro- or nano-particles | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1647263-A1 | Double chamber aerosol device comprising electrophilic monomers and use for the cosmetic treatment of hair | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1647261-A1 | Composition for the treatment of keratinous material based on electrophilic monomers and salts | L'OREAL (FR) | 2006-04-19 | — | — | EP | disclosed |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038218-A1 | Cosmetic composition comprising at least one electrophilic monomer, at least one fluoro compound and at least one liquid organic solvent | KRT18, CUTA, FLNA | ZDHHC20 1208/4885ZDHHC2 1900/4885TSHR 3393/4885 |
| US-20070251028-A1 | Dyeing composition comprising at least one electrophilic monomer, one hydrophilic dye and one liquid organic solvent | KRT18, DSG1, IK | ZDHHC20 2110/4885ZDHHC2 1978/4885TSHR 4753/4885 |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | HOGA1, OAT, SUCLG1 | ZDHHC20 798/4885ZDHHC2 1202/4885TSHR 4459/4885 |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | KRT18, DSG1, DSC1 | ZDHHC20 952/4885ZDHHC2 1194/4885TSHR 4360/4885 |
| US-20070251027-A1 | Dyeing composition comprising at least one soluble fluorescent compound, at least one electrophilic monomer and at least one liquid organic solvent | KRT18, VIM, DSG1 | ZDHHC20 2489/4885ZDHHC2 2739/4885TSHR 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.