Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396060 | 1.00 | ZDHHC20 (0.45) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL9396161 | 0.95 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL307977 | 0.92 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL515065 | 0.91 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL27994509 | 0.80 | ZDHHC20 (0.43) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL1285506 | 0.80 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL14844645 | 0.80 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL9396230 | 0.79 | — | — | |
| SCHEMBL9396652 | 0.79 | — | — | |
| SCHEMBL851909 | 0.79 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387706-B1 | Oxygen permeable hard contact lens | KURARAY CO (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5162391-A | Copolymer of Siloxanyalkylacrylamide of a Fluoro Monomer | KURARAY CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0387706-A2 | Oxygen permeable hard contact lens | KURARAY CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |