Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.49 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396182 | 0.95 | ZDHHC20 (0.45) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL9396060 | 0.95 | ZDHHC20 (0.45) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL307977 | 0.87 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL515065 | 0.85 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL851909 | 0.83 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL851109 | 0.81 | ZDHHC20 (0.54) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL31384454 | 0.81 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL761985 | 0.80 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL4349259 | 0.80 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL9396624 | 0.77 | KDM4E (0.31) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387706-B1 | Oxygen permeable hard contact lens | KURARAY CO (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5162391-A | Copolymer of Siloxanyalkylacrylamide of a Fluoro Monomer | KURARAY CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0387706-A2 | Oxygen permeable hard contact lens | KURARAY CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |