SCHEMBL93962

SCHEMBL93962

Nc1ccn(C2CCCC2)c(=O)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
PDE3A Q14432 3/20 0.46
CACNA1F O60840 2/20 0.46
ALB P02768 2/20 0.46
MAPT P10636 2/20 0.46
CACNA1D Q01668 2/20 0.46
CACNA1S Q13698 2/20 0.46
CACNA1C Q13936 2/20 0.46
THRB P10828 1/20 0.44
MTOR P42345 1/20 0.44
MDM2 Q00987 1/20 0.44
NCOA1 Q15788 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
PDE4D Q08499 1/20 0.42
SLC29A1 Q99808 1/20 0.42
POLG P54098 2/20 0.38
ST6GAL1 P15907 1/20 0.38
HCAR1 Q9BXC0 2/20 0.37
POLB P06746 2/20 0.36
NT5E P21589 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11718779 0.98 LMNA (0.45) LMNAPDE3ACACNA1FALBMAPT
SCHEMBL11715163 0.98 LMNA (0.45) LMNAPDE3ACACNA1FALBMAPT
SCHEMBL3703275 0.96 LMNA (0.46) LMNAPDE3ACACNA1FALBMAPT
SCHEMBL11716186 0.93 LMNA (0.48) LMNAPDE3ACACNA1FALBMAPT
SCHEMBL27292843 0.85 HTR3E (0.40) LMNAPDE3ACACNA1FALBMAPT
SCHEMBL26171208 0.85 PDE3A (0.43) LMNAPDE3ACACNA1FALBMAPT
SCHEMBL27283810 0.83 HTR3E (0.44) LMNAPDE3ACACNA1FALBMAPT
SCHEMBL4919650 0.81 LMNA (0.43) LMNAPDE3ACACNA1FALBMAPT
SCHEMBL9310528 0.77 LMNA (0.54) LMNAPDE3ACACNA1FALBMAPT
SCHEMBL22198551 0.77 LMNA (0.40) LMNAPDE3ACACNA1FALBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12161726-B2 Biomimetic vesicles and uses thereof OHIO STATE INNOVATION FOUNDATION (US) 2024-12-10 US claimed
US-20230346972-A1 BIOMIMETIC VESICLES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION 2023-11-02 US claimed
US-20210205473-A1 BIOMIMETIC VESICLES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION 2021-07-08 US claimed
EP-3796895-A1 BIOMIMETIC VESICLES AND USES THEREOF Ohio State Innovation Foundation (US) 2021-03-31 EP claimed
JP-2011528275-A 2011-11-17 JP claimed
EP-2313122-A1 DRUG DELIVERY MEDICAL DEVICE Micell Technologies, Inc. (US) 2011-04-27 EP claimed
WO-2010009335-A1 DRUG DELIVERY MEDICAL DEVICE MICELL TECHNOLOGIES, INC. (US) 2010-01-21 WO claimed
US-20050049220-A1 Dosing regimen for Flaviviridae therapy PHARMASSET, INC. 2005-03-03 US claimed
WO-2005018330-A1 DOSING REGIMEN FOR FLAVIVIRIDAE THERAPY PHARMASSET, INC. (US) 2005-03-03 WO claimed
WO-1997048391-A2 METHODS AND COMPOSITIONS COMPRISING R-IBUPROFEN ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE (US) 1997-12-24 WO claimed
EP-0393575-B1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent SEARLE & CO (US) 1994-03-16 EP claimed
EP-0393575-A1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent G.D. Searle & Co. (US) 1990-10-24 EP claimed
EP-4746875-A2 CARCINOGENESIS REDUCTION WITH PENTAAZA MACROCYCLIC RING COMPLEX Galera Labs, LLC (US) 2026-05-27 EP disclosed
CN-122074087-A Reverse transcription mediated gene editing system and use thereof 阿伯生物技术公司 2026-05-22 CN disclosed
US-20260137817-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX GALERA LABS LLC (US) 2026-05-21 US disclosed
US-20260108480-A1 METHODS FOR INDUCING PROLIFERATION OF STEM CELLS UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2026-04-23 US disclosed
WO-1997048391-A2 METHODS AND COMPOSITIONS COMPRISING R-IBUPROFEN ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE (US) 1997-12-24 WO disclosed
EP-0393575-B1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent SEARLE & CO (US) 1994-03-16 EP disclosed
EP-0393575-A1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent G.D. Searle & Co. (US) 1990-10-24 EP disclosed
US-4016267-A BACTERICIDES HOFFMANN-LA ROCHE INC. (US) 1977-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108480-A1 METHODS FOR INDUCING PROLIFERATION OF STEM CELLS CYP4X1, SLC6A7, ZFX LMNA 3499/4885PDE3A 2439/4885CACNA1F 122/4885
US-20050049220-A1 Dosing regimen for Flaviviridae therapy HAVCR2, EIF2AK2, CYP3A5 LMNA 3687/4885PDE3A 2979/4885CACNA1F 4820/4885
US-20260137817-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX CD274, PDCD1, PDCD1LG2 LMNA 3759/4885PDE3A 4719/4885CACNA1F 3765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.