Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398433 | 0.97 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9398295 | 0.88 | TSHR (0.53) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9398318 | 0.86 | LMNA (0.62) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9398483 | 0.85 | KDM4E (0.50) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9397177 | 0.84 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9398482 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9397291 | 0.84 | LMNA (0.65) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9397162 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9398430 | 0.82 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL9398241 | 0.82 | TSHR (0.59) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |