Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398318 | 0.98 | LMNA (0.62) | LMNAKDM4EPKMKMT2AMEN1 | |
| SCHEMBL9397256 | 0.87 | PKM (0.56) | LMNAKDM4EPKMKMT2AMEN1 | |
| SCHEMBL9397286 | 0.86 | LMNA (0.63) | LMNAKDM4EPKMKMT2AMEN1 | |
| SCHEMBL9398433 | 0.86 | ALDH1A1 (0.70) | LMNAKDM4EPKMKMT2AMEN1 | |
| SCHEMBL9198833 | 0.85 | PKM (0.53) | LMNAKDM4EPKMKMT2AMEN1 | |
| SCHEMBL9198535 | 0.84 | KDM4E (0.68) | LMNAKDM4EPKMKMT2AMEN1 | |
| SCHEMBL9397181 | 0.84 | ALDH1A1 (0.67) | LMNAKDM4EPKMKMT2AMEN1 | |
| SCHEMBL9192720 | 0.84 | KDM4E (0.67) | LMNAKDM4EPKMKMT2AMEN1 | |
| SCHEMBL9398311 | 0.83 | LMNA (0.60) | LMNAKDM4EPKMKMT2AMEN1 | |
| SCHEMBL9398253 | 0.80 | ALDH1A1 (0.58) | LMNAKDM4EPKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |