Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397144 | 0.98 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL9398253 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL9397193 | 0.87 | ALK (0.41) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9397139 | 0.85 | POLB (0.42) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9194491 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL9398295 | 0.82 | TSHR (0.53) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL9346847 | 0.81 | TSHR (0.48) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL9200976 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL9398482 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL9344872 | 0.80 | TSHR (0.53) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |