Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194491 | 0.92 | ALDH1A1 (0.55) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL9193433 | 0.89 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL9199361 | 0.87 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL9198656 | 0.83 | KDM4E (0.47) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL9397144 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL9201315 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL9200697 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL9194304 | 0.80 | LMNA (0.57) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL9198961 | 0.80 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL9397200 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471841-B1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ASAHI CHEMICAL IND (JP) | 1995-11-02 | — | — | EP | disclosed |
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |