Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | EBP | Q15125 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397139 | 0.97 | POLB (0.42) | ALKINSRPOLBALDH1A1LMNA | |
| SCHEMBL9398249 | 0.88 | ALDH1A1 (0.51) | POLBALDH1A1LMNAADRA1DADRA1A | |
| SCHEMBL9397200 | 0.87 | ALDH1A1 (0.49) | POLBALDH1A1LMNAADRA1DADRA1A | |
| SCHEMBL9397144 | 0.84 | ALDH1A1 (0.51) | POLBALDH1A1LMNAADRA1DADRA1A | |
| SCHEMBL9398291 | 0.82 | MAPT (0.43) | POLBALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL9346842 | 0.82 | HRH3 (0.40) | POLBALDH1A1LMNAADRA1AADRA1B | |
| SCHEMBL9349897 | 0.81 | SMN1; SMN2 (0.39) | ALDH1A1LMNAADRA1AKMT2ASIGMAR1 | |
| SCHEMBL9344868 | 0.80 | MAPT (0.41) | POLBALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9344884 | 0.79 | HRH3 (0.40) | ALDH1A1ADRA1AADRA1BKMT2AHPGD | |
| SCHEMBL9398477 | 0.79 | SMN1; SMN2 (0.46) | POLBALDH1A1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |