Tisopurine

Tisopurine

SCHEMBL93974

Sc1ncnc2[nH]ncc12

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 2/20 0.61
RET P07949 1/20 0.61
PI4KA P42356 1/20 0.61
LRRK2 Q5S007 1/20 0.61
PI4K2B Q8TCG2 1/20 0.61
PI4K2A Q9BTU6 1/20 0.61
PI4KB Q9UBF8 1/20 0.61
PDPK1 O15530 1/20 0.55
CHEK1 O14757 1/20 0.53
AURKA O14965 1/20 0.53
MAPK1 P28482 3/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGDS O60760 1/20 0.47
MKNK1 Q9BUB5 4/20 0.45
CYP1A2 P05177 2/20 0.45
CCNT1 O60563 1/20 0.45
CCNA2 P20248 1/20 0.45
CDK2 P24941 1/20 0.45
CDK9 P50750 1/20 0.45
CCNA1 P78396 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tisopurine SCHEMBL31313977 1.00 XDH (0.61) XDHRETPI4KALRRK2PI4K2B
Tisopurine SCHEMBL8628339 0.98 XDH (0.59) XDHRETPI4KALRRK2PI4K2B
Tisopurine SCHEMBL8628336 0.98 XDH (0.59) XDHRETPI4KALRRK2PI4K2B
SCHEMBL11363 0.76 XDH (1.00) XDHRETPI4KALRRK2PI4K2B
SCHEMBL28839743 0.76 XDH (0.63) XDHRETPI4KALRRK2PI4K2B
SCHEMBL30763272 0.76 XDH (0.63) XDHRETPI4KALRRK2PI4K2B
SCHEMBL29351045 0.76 XDH (1.00) XDHRETPI4KALRRK2PI4K2B
Hydrochloric Acid SCHEMBL14742346 0.74 XDH (0.96) XDHRETPI4KALRRK2PI4K2B
SCHEMBL11218 0.74 XDH (0.61) XDHRETPI4KALRRK2PI4K2B
SCHEMBL15504523 0.74 XDH (0.61) XDHRETPI4KALRRK2PI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3923953-A2 PYRIMIDINE DERIVATIVE CONTAINING COMPOSITIONS CHEMISTRYRX (US) 2021-12-22 EP claimed
WO-2020168358-A2 PYRIMIDINE DERIVATIVE CONTAINING COMPOSITIONS CHEMISTRYRX (US) 2020-08-20 WO claimed
US-20200253994-A1 PYRIMIDINE DERIVATIVE CONTAINING COMPOSITIONS CHEMISTRYRX (US) 2020-08-13 US claimed
US-7579134-B2 cover layer comprises polyamic acid precursor curable to an adhesive polyimide base polymer and an ethylenically unsaturated photo-monomer; avoiding unwanted curling of a flexible printed circuit E. I. DUPONT DE NEMOURS AND COMPANY (US) 2009-08-25 US claimed
US-20060210819-A1 Polyimide composite coverlays and methods and compositions relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2006-09-21 US claimed
US-6846525-B2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 2005-01-25 US claimed
US-20040202825-A1 RECORDING SHEETS CONTAINING PURINE, PYRIMIDINE, BENZIMIDAZOLE, IMIDAZOLIDINE, URAZOLE, PYRAZOLE, TRIAZOLE, BENZOTRIAZOLE, TETRAZOLE, AND PYRAZINE COMPOUNDS XEROX CORPORATION 2004-10-14 US claimed
EP-1431984-A1 Polymer resistor composition having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E. I. du Pont de Nemours and Company (US) 2004-06-23 EP claimed
US-20040113127-A1 Resistor compositions having a substantially neutral temperature coefficient of resistance and methods and compositions relating thereto E.I. DU PONT DE NEMOURS AND COMPANY 2004-06-17 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
WO-2024101219-A1 COLORED CURABLE RESIN COMPOSITION, COLOR FILTER, DISPLAY DEVICE, AND SOLID-STATE IMAGING ELEMENT 住友化学株式会社 2024-05-16 WO disclosed
US-3968226-A 3-Heterocyclic thiomethylcephalosporins as antibacterial agents SMITHKLINE CORPORATION (US) 1976-07-06 US disclosed