Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584150 | 0.79 | ALDH1A1 (0.47) | KMT2AMEN1LMNACYP2C19HIF1A | |
| SCHEMBL11811515 | 0.78 | NPC1 (0.43) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL22095153 | 0.76 | CYP2C19 (0.47) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL28434224 | 0.76 | RIPK1 (0.44) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL1697396 | 0.75 | LMNA (0.47) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL20475967 | 0.75 | LMNA (0.47) | RIPK1KMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL2089572 | 0.75 | CYP1A2 (0.50) | KMT2ACYP2C19HIF1APOLBALDH1A1 | |
| SCHEMBL2089573 | 0.75 | CYP1A2 (0.50) | KMT2ACYP2C19HIF1APOLBALDH1A1 | |
| SCHEMBL754265 | 0.75 | CYP1A2 (0.50) | KMT2ACYP2C19HIF1APOLBALDH1A1 | |
| SCHEMBL8034023 | 0.74 | RIPK1 (0.45) | RIPK1KMT2AMEN1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027955-A1 | INTERMEDIATES AND PROCESS OF MAKING DIPEPTIDE ISOSTERES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | claimed |
| WO-1994027955-A1 | INTERMEDIATES AND PROCESS OF MAKING DIPEPTIDE ISOSTERES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |